Atropine Sulfate
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Atropine Sulfate: Atropine is a naturally occurring
agent in the plant Atropa belladonna (deadly nightshade). It is
classified as an Anticholinergic agent or antimuscarinic, which
blocks the action of acetylcholine in the parasympathetic nervous
system. The effects of this inhibition include mydriasis (dilation)
of the pupils and increased intraocular pressure in patients with
glaucoma; dry, tenacious secretions of nose, mouth, throat, and
bronchi; decreased motility and secretions of the gastrointestinal
tract; heart rate increases; and decreased sweating.
Atropine may be given presurgery to reduce salivation and bronchial
secretions, minimize bradycardia during intubation or for the
treatment of pylorospasms and spastic conditions. It is indicated
specifically for symptomatic bradycardia related to poor perfusion
and hypotension, relative or vagally mediated bradycardia. It
is also commonly used during advanced cardiac life support for
asystole or pulseless electrical activity.
