Administration of Dipivan (propofol) through TCI is currently
restricted to induction and maintenance of general anaesthesia
in adults. It is not recommended for use in ICU sedation or
concious sedation, or in children.
Diprivan (propofol) may be administered by TCI only with a
`Diprifusor` TCI system incorporating `Diprifusor` TCI software.
See the Diprifusor Monograph for more information.
Target control should be titrated against patient response
to achieve required depth of anaesthesia. Guidelines are given
below.
Induction of Anaesthesia
Patient Type
Adult <55yrs
Target Blood Propofol Concentration
4-8mcg/mL
Notes
Initial target of 4mcg/mL for premedicated patients. Initial
target of 6mcg/mL for unpremedicated patients
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Patient Type
Adult >55yrs and ASA III/IV
Notes
Lower initial target should be used. Target concentrations can
be increased in steps of 0.5-1.0mcg/mL over 1 minute intervals
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Maintenance of Anaesthesia Target Blood Propofol Concentration
3-6mcg/mL
Notes
Can be reduced by supplementary analgesia requirements
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Patient Type
Wakening
Target Blood Propofol Concentration
1.0-2.0mcg/mL
NOTE: For full details of product indications see local prescribing
information
source: anaesthesia-az.com
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